Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-8-11
pubmed:abstractText
The effect of intracellular calcium injection on steady state membrane currents was studied in isolated guinea-pig ventricular cells with a single-electrode voltage clamp method. When the membrane potential was clamped at the resting potential, an intracellular injection of Ca induced an inward current. The steady state current-voltage (I-V) curves before and after Ca injection crossed at around -22 mV. Above this potential, Ca increased the current in the outward direction. A linear relationship was observed between the current mediated by the increase of intracellular Ca and membrane potentials from -60 to +10 mV. This current component may correspond to the Ca-activated non-selective cation channels recorded by the patch clamp technique (Colquhoun et al., 1981).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0031-6768
pubmed:author
pubmed:issnType
Print
pubmed:volume
397
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
81-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Effects of intracellular calcium injection on steady state membrane currents in isolated single ventricular cells.
pubmed:publicationType
Journal Article, In Vitro