Linked Life Data

6337003

Source:http://linkedlifedata.com/resource/pubmed/id/6337003

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-3-17
pubmed:abstractText
A single dose of guanabenz was examined for effects upon blood pressure, heart rate, plasma catecholamines, and plasma renin activity in a randomized, double-blind, crossover design. Eight patients were studied when supine, standing, and during submaximal exercise. Guanabenz reduced blood pressure in subjects who were supine or standing. Heart rate was lowered only in the supine subjects. Guanabenz induced reduction in plasma catecholamines subjects in all positions and the reduction correlated with the placebo level for both norepinephrine and epinephrine. Plasma renin activity was not significantly affected by guanabenz. The results indicate that the central alpha-agonist action of guanabenz reduces sympathoadrenal function to a greater extent in hyperadrenergic hypertensive patients than in those without this disorder.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0009-9236
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
151-5
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Effect of guanabenz on blood pressure responses to posture and exercise.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Randomized Controlled Trial, Research Support, Non-U.S. Gov't