Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-8-13
pubmed:abstractText
The binding of [3H]N6-(L-Phenylisopropyl) adenosine (L-PIA) to membrane preparations of whole brains from normal male Sprague-Dawley rats 12 and 84 weeks of age, respectively, was examined. Two populations of binding sites, probably corresponding to A1 and A2 adenosine receptors, were detected in both young and old rats. No statistically significant differences between young and old rats were detected but both the numbers of binding sites (Bmax) and dissociation constants (KD) for both high and low affinity binding sites were greater in 84 week old rats. These results were compared to earlier studies of adenosine receptors and related to previously reported changes in sleep with aging in rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0197-4580
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61-2
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
[3H]N6-(L-Phenylisopropyl) adenosine binding in brains from young and old rats.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.