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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1984-6-14
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pubmed:abstractText |
Patients with active pulmonary sarcoidosis underwent bronchoalveolar lavage, gallium scan, and serum angiotensin-converting enzyme (ACE) level determination prior to treatment with corticosteroids. Pulmonary function was tested before and after therapy. Increase in vital capacity after treatment ranged from 40 to 1,030 ml; 12 of the 16 patients studied had an increase of more than 200 ml. There was a close correlation between the percentage uptake of gallium scan and the increase of the vital capacity after therapy (r = 0.95, p less than 0.01). There was no relationship between the percentage of lymphocytes obtained on lavage and the changes in vital capacity with therapy (r = 0.05). There was a positive correlation between the changes in vital capacity and the ratio of T4(+):T8(+)lymphocytes (r = 0.62, p less than 0.05) and number of T4 (+) lymphocytes (r = 0.92, p less than 0.01) in the bronchoalveolar fluid. There was a low correlation between the pretreatment ACE level and the change in vital capacity (r = 0.368, p greater than 0.05).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0003-0805
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
129
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
676-81
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:6326626-Acetylcholinesterase,
pubmed-meshheading:6326626-Adrenal Cortex Hormones,
pubmed-meshheading:6326626-Adult,
pubmed-meshheading:6326626-Antibodies, Monoclonal,
pubmed-meshheading:6326626-Female,
pubmed-meshheading:6326626-Gallium Radioisotopes,
pubmed-meshheading:6326626-Humans,
pubmed-meshheading:6326626-Lung,
pubmed-meshheading:6326626-Lung Diseases,
pubmed-meshheading:6326626-Male,
pubmed-meshheading:6326626-Middle Aged,
pubmed-meshheading:6326626-Peptidyl-Dipeptidase A,
pubmed-meshheading:6326626-Prognosis,
pubmed-meshheading:6326626-Pulmonary Alveoli,
pubmed-meshheading:6326626-Sarcoidosis,
pubmed-meshheading:6326626-Serum Albumin,
pubmed-meshheading:6326626-T-Lymphocytes,
pubmed-meshheading:6326626-Therapeutic Irrigation,
pubmed-meshheading:6326626-Time Factors,
pubmed-meshheading:6326626-Vital Capacity
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pubmed:year |
1984
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pubmed:articleTitle |
Comparison of gallium-67 scanning, bronchoalveolar lavage, and serum angiotensin-converting enzyme levels in pulmonary sarcoidosis. Predicting response to therapy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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