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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5 Pt.2
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|
pubmed:dateCreated |
1977-1-29
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|
pubmed:abstractText |
F(ab')2 fragments of rabbit antibodies specific for human B lymphocytes will block human anti-B lymphocyte alloantibodies. F(ab')2 of anti-beta2m will block HLA alloantibodies. The F(ab')2 fragments can be used to improve the typing of B cell lines and certain leukemia cells which express both HLA and B lymphocyte alloantigens. Pretreatment of these cells with anti-beta2m F(ab')2 preparations allows the observation of B cell alloantigen reactions independently of HLA reactions. Similar use of rabbit anti-B cell F (ab')2 allows HLA reactions to be observed free from the "extra reactions" caused by B alloantibodies that are present in many HLA typing sera.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Nov
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|
pubmed:issn |
0022-1767
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
117
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|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2040-2
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
|
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pubmed:year |
1976
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pubmed:articleTitle |
Blocking of HLA and B lymphocyte alloantigens with F (ab')2 fragments of rabbit antibodies.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
