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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1983-3-17
|
| pubmed:abstractText |
We evaluated the relationship of rate-dependent changes in atrial refractoriness to atrial vulnerability in 39 patients. Vulnerability was considered present when sustained atrial tachyarrhythmias, lasting longer than 1 minute, could be provoked with one to three extra stimuli. Adaptation of atrial refractory period duration to rate was defined as: normal: steep rate reduction with a linear correlation slope value of 0.08 or more; non-adaptation: absence of rate reduction, the slope value being 0 to 0.01; poor adaptation: slight reduction with rate, the slope having values of 0.02 to 0.07. Increased vulnerability was demonstrable in 16 of 17 patients with non-adaptation of the effective refractory period (ERP), and in 10 of 10 with a similar defect of the functional refractory period (FRP); in the intermediate category (poor adaptation) the results for ERP and FRP were 7/11 and 5/6. By way of contrast when both measurements showed normal adaptation, vulnerability was elicited in 2/9 patients. The significance between these groups showed P less than 0.005. Of 17 patients with atrial arrhythmia by Holter, 14 showed poor or non-adaptation of the ERP. It is suggested that poor or absent rate adaptation of the atrial refractory period, and a propensity to atrial fibrillation or flutter, constitute a clinical entity not previously described.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0167-5273
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
179-97
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6185445-Adolescent,
pubmed-meshheading:6185445-Adult,
pubmed-meshheading:6185445-Aged,
pubmed-meshheading:6185445-Arrhythmias, Cardiac,
pubmed-meshheading:6185445-Atrial Fibrillation,
pubmed-meshheading:6185445-Cardiac Complexes, Premature,
pubmed-meshheading:6185445-Cardiomyopathies,
pubmed-meshheading:6185445-Cardiovascular Diseases,
pubmed-meshheading:6185445-Electrophysiology,
pubmed-meshheading:6185445-Female,
pubmed-meshheading:6185445-Heart,
pubmed-meshheading:6185445-Heart Atria,
pubmed-meshheading:6185445-Heart Rate,
pubmed-meshheading:6185445-Humans,
pubmed-meshheading:6185445-Male,
pubmed-meshheading:6185445-Middle Aged,
pubmed-meshheading:6185445-Neural Conduction,
pubmed-meshheading:6185445-Refractory Period, Electrophysiological
|
| pubmed:year |
1982
|
| pubmed:articleTitle |
Failure in the rate adaptation of the atrial refractory period: its relationship to vulnerability.
|
| pubmed:publicationType |
Journal Article
|