Linked Life Data

6159813

Source:http://linkedlifedata.com/resource/pubmed/id/6159813

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-1-26
pubmed:abstractText
Human gene mapping is concerned with the assignment of individual genes to specific parts of chromosomes. The rapid progress in this field has shown the importance of genetics to human biology and to clinical medicine. Several approaches are available for expanding the human gene map. The gene dosage approach was used in the mapping of the esterase D and retinoblastoma locus on the long arm of chromosome 13. The principles behind kindred linkage analysis and the application of somatic cell hybridization techniques are examined in relation to human gene mapping. Recent data on the steroid sulfatase gene suggest that not all X-linked genes are susceptible to inactivation. Several clinical applications of human gene mapping and linkage information are presented. With the application of current molecular techniques, the human gene map may be substantially completed by the end of the century.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0003-4819
pubmed:issnType
Print
pubmed:volume
93
pubmed:owner
NLM
pubmed:pagination
469-79
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Human gene mapping, genetic linkage, and clinical applications.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review