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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1984-7-9
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pubmed:abstractText |
Somatostatin and several analogues were injected into rat striatum and their effects on dopamine, serotonin and their metabolites were examined at 1 h. Somatostatin induced a dose-dependent increase in dopamine turnover in the ipsilateral striatum accompanied by a reduction in turnover on the contralateral side. There was no effect on serotonin turnover. Long-acting somatostatin analogues (D-Trp-8-somatostatin, SMS-201-995) had similar effects. These results suggest that somatostatin is involved in local regulation of striatal dopaminergic transmission and that it plays a role in regulation of dopamine release in the contralateral striatum.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
24
|
pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
271-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6145120-Animals,
pubmed-meshheading:6145120-Catecholamines,
pubmed-meshheading:6145120-Chromatography, High Pressure Liquid,
pubmed-meshheading:6145120-Corpus Striatum,
pubmed-meshheading:6145120-Electrochemistry,
pubmed-meshheading:6145120-Male,
pubmed-meshheading:6145120-Rats,
pubmed-meshheading:6145120-Rats, Inbred Strains,
pubmed-meshheading:6145120-Somatostatin
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pubmed:year |
1984
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pubmed:articleTitle |
The effect of somatostatin on striatal catecholamines.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|