| pubmed-article:6115714 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6115714 | lifeskim:mentions | umls-concept:C0012984 | lld:lifeskim |
| pubmed-article:6115714 | lifeskim:mentions | umls-concept:C1522564 | lld:lifeskim |
| pubmed-article:6115714 | lifeskim:mentions | umls-concept:C0225897 | lld:lifeskim |
| pubmed-article:6115714 | lifeskim:mentions | umls-concept:C0205094 | lld:lifeskim |
| pubmed-article:6115714 | lifeskim:mentions | umls-concept:C0026029 | lld:lifeskim |
| pubmed-article:6115714 | lifeskim:mentions | umls-concept:C0205307 | lld:lifeskim |
| pubmed-article:6115714 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:6115714 | lifeskim:mentions | umls-concept:C0542339 | lld:lifeskim |
| pubmed-article:6115714 | lifeskim:mentions | umls-concept:C1705241 | lld:lifeskim |
| pubmed-article:6115714 | lifeskim:mentions | umls-concept:C0677535 | lld:lifeskim |
| pubmed-article:6115714 | lifeskim:mentions | umls-concept:C1705242 | lld:lifeskim |
| pubmed-article:6115714 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:6115714 | pubmed:dateCreated | 1981-11-24 | lld:pubmed |
| pubmed-article:6115714 | pubmed:abstractText | Myocardial beta-adrenoceptor binding was investigated, with (-)3H dihydroalprenolol as radioligand, in microsomes derived from anterior (ALV) and inferior (ILV) myocardial wall sections of the canine left ventricle. Characterisation of specific binding sites revealed a hierarchy of myocardial beta-adrenoceptor binding with greater binding occurring to the anterior than the inferior wall of the left ventricle, under identical experimental conditions. Equilibrium analysis by Scatchard plots suggested a significant (P less than 0.01) difference in the number of receptors (Bmax ALV = 70 fmol . mg-1 protein vs Bmax ILV = 37 fmol . mg-1 protein) with no alteration in the binding affinity of the receptors (KDALV = 10.1 nmol . litre-1 vs KDILV = 6.7 nmol . litre-1). Such differences in the extent of binding of beta-adrenoreceptors in cardiac muscle may be of physiological and pathological significance and may account for the heterogeneity of regional autonomic responses in the heart. | lld:pubmed |
| pubmed-article:6115714 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6115714 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6115714 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6115714 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6115714 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6115714 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6115714 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6115714 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6115714 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6115714 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6115714 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:6115714 | pubmed:issn | 0008-6363 | lld:pubmed |
| pubmed-article:6115714 | pubmed:author | pubmed-author:ShellW EWE | lld:pubmed |
| pubmed-article:6115714 | pubmed:author | pubmed-author:RoseD MDM | lld:pubmed |
| pubmed-article:6115714 | pubmed:author | pubmed-author:BurnamM HMH | lld:pubmed |
| pubmed-article:6115714 | pubmed:author | pubmed-author:SethnaD HDH | lld:pubmed |
| pubmed-article:6115714 | pubmed:author | pubmed-author:SternC SCS | lld:pubmed |
| pubmed-article:6115714 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6115714 | pubmed:volume | 15 | lld:pubmed |
| pubmed-article:6115714 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6115714 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6115714 | pubmed:pagination | 239-44 | lld:pubmed |
| pubmed-article:6115714 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:6115714 | pubmed:meshHeading | pubmed-meshheading:6115714-... | lld:pubmed |
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| pubmed-article:6115714 | pubmed:meshHeading | pubmed-meshheading:6115714-... | lld:pubmed |
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| pubmed-article:6115714 | pubmed:meshHeading | pubmed-meshheading:6115714-... | lld:pubmed |
| pubmed-article:6115714 | pubmed:meshHeading | pubmed-meshheading:6115714-... | lld:pubmed |
| pubmed-article:6115714 | pubmed:meshHeading | pubmed-meshheading:6115714-... | lld:pubmed |
| pubmed-article:6115714 | pubmed:meshHeading | pubmed-meshheading:6115714-... | lld:pubmed |
| pubmed-article:6115714 | pubmed:meshHeading | pubmed-meshheading:6115714-... | lld:pubmed |
| pubmed-article:6115714 | pubmed:year | 1981 | lld:pubmed |
| pubmed-article:6115714 | pubmed:articleTitle | Differences in beta-adrenoceptor binding in anterior and inferior myocardial wall microsomes of normal canine left ventricle. | lld:pubmed |
| pubmed-article:6115714 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6115714 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6115714 | lld:pubmed |
