|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1984-10-19
|
|
pubmed:abstractText |
Lymphocyte subpopulations in the blood of cardiac transplant recipients were monitored by single and double marker rosetting tests; using monoclonal antibodies to monomorphic determinants on T cells and 'Ia' antigens. Elevated absolute numbers and percentages of TIa+ cells were found in association with primary cytomegalovirus (CMV), and reactivation of Epstein-Barr virus or Herpes simplex virus. Serial tests showed that in primary CMV TIa+ cells peaked before the maximal IgM and IgG anti-viral titres measured by ELISA. Infection related antiglobulin levels increased in parallel with anti-viral IgM in primary CMV infections. Intravenous methylprednisone and blood transfusions selectively depressed TIa+ cell levels without affecting antibody titres. These results show that patients on maintenance immunosuppression of cyclosporin A and steroids can successfully mount T cell and antibody responses to herpes virus infections.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-152800,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-215109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-355118,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-4169033,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6109048,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6114256,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6251132,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6251140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6255978,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6256660,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6274969,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6292304,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6296313,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6299633,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6302219,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6448901,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6456093,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-6996766,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6088138-7351481
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0009-9104
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
57
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
671-8
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:6088138-Antibodies, Viral,
pubmed-meshheading:6088138-Cytomegalovirus Infections,
pubmed-meshheading:6088138-Heart Transplantation,
pubmed-meshheading:6088138-Herpesviridae Infections,
pubmed-meshheading:6088138-Histocompatibility Antigens Class II,
pubmed-meshheading:6088138-Humans,
pubmed-meshheading:6088138-Immunosuppression,
pubmed-meshheading:6088138-Leukocyte Count,
pubmed-meshheading:6088138-Lymphocyte Activation,
pubmed-meshheading:6088138-Male,
pubmed-meshheading:6088138-Postoperative Complications,
pubmed-meshheading:6088138-Rosette Formation,
pubmed-meshheading:6088138-T-Lymphocytes
|
|
pubmed:year |
1984
|
|
pubmed:articleTitle |
Immune responses in cardiac transplantation. I. Detection of activated TIa+ cells in the blood during herpes virus infections.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
