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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3778
|
| pubmed:dateCreated |
1967-7-1
|
| pubmed:abstractText |
The excretion of oxypurine metabolites in urine of patients with congenital hyperuricosuria exceeds, on a creatinine basis, that observed in any previously recognized metabolic anomaly. The ratio of hypoxanthine to xanthine is from 2:1 to 3:1 and results from increased hypoxanthine excretion, in contrast to other hyperuricosuric conditions where ratios of less than one have been reported. Administration of allopurinol (a xanthine-oxidase inhibitor) reduces the excretion of uric acid but results in an equivalent increase in xanthine and hypoxanthine. These features appear to be unique to congenital hyper-uricosuria.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0036-8075
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
26
|
| pubmed:volume |
156
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1122-3
|
| pubmed:dateRevised |
2007-8-17
|
| pubmed:meshHeading |
pubmed-meshheading:6024192-Allopurinol,
pubmed-meshheading:6024192-Child,
pubmed-meshheading:6024192-Child, Preschool,
pubmed-meshheading:6024192-Humans,
pubmed-meshheading:6024192-Hypoxanthines,
pubmed-meshheading:6024192-Purine-Pyrimidine Metabolism, Inborn Errors,
pubmed-meshheading:6024192-Uric Acid,
pubmed-meshheading:6024192-Xanthines
|
| pubmed:year |
1967
|
| pubmed:articleTitle |
Urinary metabolites in congenital hyperuricosuria.
|
| pubmed:publicationType |
Journal Article
|