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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7974
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pubmed:dateCreated |
1976-8-23
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pubmed:abstractText |
60 leukaemia patients with acute mylogenous leukaemia, chronic myelocytic leukaemia, acute lymphatic leukaemia, and chronic lymphocytic leukaemia were tested for five specificities of the new B-lymphocyte alloantigenic system. Two specificities of the first B-cell locus were significantly lower in frequency than in B lymphocytes from 105 controls. B-cell group 1 was found in 18% of leukaemia patients vs. 48% of controls (p less than 0.025) and B-cell group 2 was found in 0% of leukaemia patients vs 23% of controls (p less than 0.025). Group 2 was also absent in 37 cultured lymphoblastoid lines. It is suggested that resistance to B-cell leukaemia and to Epstein-Barr virus transformation in vitro may be linked to a B-lymphocyte specificity on the first B-lymphocyte locus.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
26
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1365-7
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:59011-Adult,
pubmed-meshheading:59011-B-Lymphocytes,
pubmed-meshheading:59011-Cell Line,
pubmed-meshheading:59011-Child,
pubmed-meshheading:59011-Genetic Linkage,
pubmed-meshheading:59011-Humans,
pubmed-meshheading:59011-Immune Adherence Reaction,
pubmed-meshheading:59011-Immunoglobulin Allotypes,
pubmed-meshheading:59011-Isoantigens,
pubmed-meshheading:59011-Leukemia,
pubmed-meshheading:59011-Leukemia, Lymphoid,
pubmed-meshheading:59011-Leukemia, Myeloid,
pubmed-meshheading:59011-Leukemia, Myeloid, Acute
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pubmed:year |
1976
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pubmed:articleTitle |
The absence of B-cell antigen B2 from leukaemia cells and lymphoblastoid cell lines.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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