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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1980-1-28
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pubmed:abstractText |
Twenty-two preterm infants of gestational age 26 to 34 weeks were treated with amikacin for suspected bacterial infection, using a dose of 7.5 mg/kg, 12-hourly, intra muscularly. Blood levels were measured using a radio-immunoassay kit capable of giving results within 4 h. One-hour peak levels showed wide variation and the mean level one hour after the first dose was 18.2 mg/1; in severe infections an initial loading dose of 10 mg/kg is therefore recommended. Trough levels in individual infants also varied considerably from day to day, but showed no overall accumulation. There was no obvious adverse effect on hepatic or renal function.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0305-7453
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
527-30
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:500515-Amikacin,
pubmed-meshheading:500515-Bacterial Infections,
pubmed-meshheading:500515-Female,
pubmed-meshheading:500515-Humans,
pubmed-meshheading:500515-Infant, Low Birth Weight,
pubmed-meshheading:500515-Infant, Newborn,
pubmed-meshheading:500515-Infant, Newborn, Diseases,
pubmed-meshheading:500515-Kanamycin,
pubmed-meshheading:500515-Male,
pubmed-meshheading:500515-Radioimmunoassay
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pubmed:year |
1979
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pubmed:articleTitle |
Amikacin dosage in the preterm newborn.
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pubmed:publicationType |
Journal Article
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