rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1975-10-10
|
pubmed:abstractText |
The uptake of L-tryptophan by chicken erythrocytes is stimulated by the presence of human plasma; however, there is no difference between the stimulation caused by plasmas of normal, chronic hospitalized nonschizophrenic, or chronic hospitalized schizophrenic subjects. Human plasma in general contains a complement-dependent antibody which reacts with an antigen present in the membrane of chicken erythrocytes resulting in hemolysis. Hemolysis can be maintained at a constant level by certain concentrations of Ca++ ion, the addition of which resulted in a gradual increase in tryptophan uptake. The calcium effect is probably due to the fact that the metal acts as a cofactor or modifier of component(s) of plasma causing higher uptake. The data indicate that hemolysis is not determining uptake of tryptophan by chicken erythrocytes.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0006-3223
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
10
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
303-14
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:49200-Aged,
pubmed-meshheading:49200-Alpha-Globulins,
pubmed-meshheading:49200-Animals,
pubmed-meshheading:49200-Calcium,
pubmed-meshheading:49200-Chickens,
pubmed-meshheading:49200-Complement System Proteins,
pubmed-meshheading:49200-Edetic Acid,
pubmed-meshheading:49200-Erythrocytes,
pubmed-meshheading:49200-Guinea Pigs,
pubmed-meshheading:49200-Hemolysis,
pubmed-meshheading:49200-Humans,
pubmed-meshheading:49200-Male,
pubmed-meshheading:49200-Mental Disorders,
pubmed-meshheading:49200-Middle Aged,
pubmed-meshheading:49200-Plasma,
pubmed-meshheading:49200-Schizophrenia,
pubmed-meshheading:49200-Temperature,
pubmed-meshheading:49200-Tryptophan
|
pubmed:year |
1975
|
pubmed:articleTitle |
Validity of plasma factor in schizophrenia as measured by tryptophan uptake.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
|