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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1979-11-21
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pubmed:abstractText |
Tetrabenazine evoked a biphasic response in rectal temperature of the rat following intraperitoneal administration of 4.4--70.0 mg/kg. The initial hyperthermia was inversely related to the dose while the subsequent hypothermia was dose-dependent. This biphasic effect on temperature was similar to that seen with THC at 0.5 mg/kg, thus adding further evidence of a similarity in the mode of action of the two drugs. In contrast, only hypothermia was evident following chlorpromazine administration.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0031-7012
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
251-6
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:482345-Animals,
pubmed-meshheading:482345-Body Temperature,
pubmed-meshheading:482345-Chlorpromazine,
pubmed-meshheading:482345-Dose-Response Relationship, Drug,
pubmed-meshheading:482345-Injections, Intraperitoneal,
pubmed-meshheading:482345-Rats,
pubmed-meshheading:482345-Rectum,
pubmed-meshheading:482345-Tetrabenazine,
pubmed-meshheading:482345-Tetrahydrocannabinol
|
pubmed:year |
1979
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pubmed:articleTitle |
Comparative effects of delta 9-tetrahydrocannabinol, tetrabenazine and chlorpromazine on rectal temperature in the rat.
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pubmed:publicationType |
Journal Article,
Comparative Study
|