rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
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pubmed:dateCreated |
1973-11-6
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pubmed:abstractText |
Ultrastructural changes in the mitochondria and other organelles in zona glomerulosa cells of the adrenal cortex were noted in rats maintained for up to 8 days on a potassium-enriched or a sodium-deficient diet. In both groups of animals, aldosterone production is known to be increased. Principal ultrastructural changes in the rats maintained on a potassium-supplemented or a sodium-deficient diet consisted of a loss of electron density of the mitochondrial matrix and a change from plate-like cristae to tubular-vesicular cristae. These changes were similar in both potassium-enriched and sodium-depleted animals after 8 days and were markedly different from control animals. Morphologic changes occurred after the initial increase in aldosterone production, which has been measured in 1 to 2 days in both sodium-depleted and potassium-enriched rats. The mitochondrial changes described are probably related to the persistent increased active steroid synthesis.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-13214007,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-13285461,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-13745140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-13764136,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-13869745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-13938767,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-14008932,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-14420649,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-4285180,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-4303948,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-4320595,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-4321989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-5009067,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-5414284,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-5541295,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-5565093,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-5565878,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-5578778,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-5695567,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-5784927,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-5865935,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4728893-6074010
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
pubmed:issn |
0002-9440
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
72
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
433-46
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pubmed:dateRevised |
2010-6-22
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pubmed:meshHeading |
pubmed-meshheading:4728893-Adrenal Glands,
pubmed-meshheading:4728893-Aldosterone,
pubmed-meshheading:4728893-Animal Nutritional Physiological Phenomena,
pubmed-meshheading:4728893-Animals,
pubmed-meshheading:4728893-Diet,
pubmed-meshheading:4728893-Endoplasmic Reticulum,
pubmed-meshheading:4728893-Golgi Apparatus,
pubmed-meshheading:4728893-Lipids,
pubmed-meshheading:4728893-Male,
pubmed-meshheading:4728893-Microscopy, Electron,
pubmed-meshheading:4728893-Mitochondria,
pubmed-meshheading:4728893-Potassium,
pubmed-meshheading:4728893-Rats,
pubmed-meshheading:4728893-Sodium,
pubmed-meshheading:4728893-Time Factors
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pubmed:year |
1973
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pubmed:articleTitle |
The ultrastructure of the adrenal zona glomerulosa of rats on patassium-supplemented or sodium-depleted diets.
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pubmed:publicationType |
Journal Article
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