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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1985-12-27
|
| pubmed:abstractText |
A quantitative histological analysis of ovaries from 3- and 5-day-old female mice heterozygous for the male-sterile reciprocal autosomal translocation, T(11;19)42H, revealed a marked reduction (by 65%) in the number of oocytes as compared to controls. These findings call into question the widely held view that chromosomal anomalies causing spermatogenic failure have no effect on oogenesis. It is suggested that during meiosis in males and females there is a mechanism operating which tends to eliminate cells which had incomplete chromosome pairing at the pachytene stage.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0022-4251
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
75
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
647-52
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:4067938-Animals,
pubmed-meshheading:4067938-Cell Count,
pubmed-meshheading:4067938-Chromosome Aberrations,
pubmed-meshheading:4067938-Chromosome Disorders,
pubmed-meshheading:4067938-Female,
pubmed-meshheading:4067938-Meiosis,
pubmed-meshheading:4067938-Mice,
pubmed-meshheading:4067938-Oocytes,
pubmed-meshheading:4067938-Ovary,
pubmed-meshheading:4067938-Translocation, Genetic
|
| pubmed:year |
1985
|
| pubmed:articleTitle |
A reciprocal autosomal translocation which causes male sterility in the mouse also impairs oogenesis.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|