Linked Life Data

3988029

Source:http://linkedlifedata.com/resource/pubmed/id/3988029

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-5-29
pubmed:abstractText
The synthesis of steroids in vitro by adrenal glands from female Lacerta vivipara J., using various labeled steroids as substrates, was studied. Effects of two enzymatic inhibitors (cyanoketone and elipten) on steroid synthesis was analyzed. As in other reptilian species, no 17-hydroxycorticosteroids were detected and the major biosynthetic pathway operating in vitro proved to be that of 17-deoxycorticosteroids. An important synthesis of an unidentified compound (X) was observed only from pregnenolone. Incubations of L. vivipara adrenal glands have been performed using [3H]pregnenolone plus [14C]progesterone at different phases of the annual cycle. Changes in adrenal steroid activity, related to season and physiological state of female, are quantitative rather than qualitative. High production in vitro of progesterone and 18-hydroxycorticosterone is associated with gestation whereas high production of deoxycorticosterone and corticosterone is observed during hibernation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0016-6480
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
In vitro steroid biosynthesis by the adrenal gland of the female Lacerta vivipara Jacquin: the metabolism of exogenous precursors.
pubmed:publicationType
Journal Article