Linked Life Data

3936258

Source:http://linkedlifedata.com/resource/pubmed/id/3936258

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1986-2-5
pubmed:abstractText
In four cases of capillarosclerosis in the urinary tract associated with analgesic (phenacetin) abuse, the basement membrane (BM) thickening was not confined to the subepithelial capillaries, but was also found around the smooth muscle cells in the luminal part of the tunica muscularis. Electron microscopy confirmed that the changes in the BM around the smooth muscle cells were similar to those seen around capillaries. This non-vascular affection of BM in the urinary tract in patients with phenacetin abuse has not been reported previously. Thus, capillarosclerosis appears to be only part of a BM disorder, that clearly diminishes in intensity with increasing distance from the lumen. It is therefore suggested that the changes are caused by some agent (possibly a metabolite) in the urine diffusing from the lumen into the wall of the urinary tract.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0174-7398
pubmed:author
pubmed:issnType
Print
pubmed:volume
408
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
173-82
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Non-epithelial basement membrane thickening in the urinary tract associated with phenacetin abuse.
pubmed:publicationType
Journal Article