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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1985-7-3
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|
pubmed:abstractText |
Pituitary-thyroid axis function and gonadotropin secretion were evaluated by a combined TRH and LHRH test in 4 newborn female infants appropriate for gestational age of mothers treated by AEDs throughout pregnancy. We found: high basal FSH levels with normal FSH reserve, normal LH-HCG levels both before and after LHRH stimulation, normal TSH and T4 levels both before and after TRH stimulation, high T3 basal values with a normal increase after TRH and low rT3 basal values. It is suggested an AED increased T4 deiodination towards T3 in the newborn liver without a marked impairment of the endocrine functions of the fetus.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0037-8771
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:day |
28
|
|
pubmed:volume |
61
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
195-8
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:3922390-Anticonvulsants,
pubmed-meshheading:3922390-Endocrine System Diseases,
pubmed-meshheading:3922390-Female,
pubmed-meshheading:3922390-Follicle Stimulating Hormone,
pubmed-meshheading:3922390-Humans,
pubmed-meshheading:3922390-Infant, Newborn,
pubmed-meshheading:3922390-Luteinizing Hormone,
pubmed-meshheading:3922390-Pregnancy,
pubmed-meshheading:3922390-Prenatal Exposure Delayed Effects,
pubmed-meshheading:3922390-Thyrotropin,
pubmed-meshheading:3922390-Thyroxine,
pubmed-meshheading:3922390-Triiodothyronine
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|
pubmed:year |
1985
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|
pubmed:articleTitle |
Effects of anticonvulsant monotherapy in pregnancy on the newborn endocrine system. Preliminary data.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
