Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1986-3-31
|
pubmed:abstractText |
8 cases were studied to determine whether immunohistochemical investigation with anti-GFAP could contribute to confirming a primary brain tumor origin for an extracranial metastasis. The materials studied consisted of 3 glioblastomas, 3 anaplastic astrocytomas, and 2 medulloblastomas, along with their extracranial metastases. GFAP could be immunohistochemically demonstrated in all 6 primary glial tumors as well as in the metastases of the 3 astrocytomas and of 2 glioblastomas. The medulloblastomas and their metastases were immunohistochemically GFAP-negative. GFAP is thus a marker for extracranial metastases of astrocytomas and glioblastomas. A negative result however does not exclude the possibility that a metastasis is of glial origin as shown by the GFAP-negative metastasis of the one glioblastoma.
|
pubmed:language |
ger
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0044-4030
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
130
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
391-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3913231-Adult,
pubmed-meshheading:3913231-Aged,
pubmed-meshheading:3913231-Antibodies,
pubmed-meshheading:3913231-Antigen-Antibody Complex,
pubmed-meshheading:3913231-Astrocytoma,
pubmed-meshheading:3913231-Brain Neoplasms,
pubmed-meshheading:3913231-Cerebellar Neoplasms,
pubmed-meshheading:3913231-Child,
pubmed-meshheading:3913231-Female,
pubmed-meshheading:3913231-Glial Fibrillary Acidic Protein,
pubmed-meshheading:3913231-Glioma,
pubmed-meshheading:3913231-Humans,
pubmed-meshheading:3913231-Immunoenzyme Techniques,
pubmed-meshheading:3913231-Male,
pubmed-meshheading:3913231-Medulloblastoma,
pubmed-meshheading:3913231-Middle Aged,
pubmed-meshheading:3913231-Neoplasm Metastasis
|
pubmed:year |
1985
|
pubmed:articleTitle |
[Significance of immunohistochemistry in neuro-oncology. I. Demonstration of glial fibrillary acid protein (GFAP) in extracranial metastases from primary brain tumors].
|
pubmed:publicationType |
Journal Article,
English Abstract
|