Linked Life Data

3815093

Source:http://linkedlifedata.com/resource/pubmed/id/3815093

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1987-4-15
pubmed:abstractText
The uptake and retention of radioactivity from [3H]2-deoxyglucose [( 3H]2-DG) was assessed in certain regions of the rat brain under basal conditions using dry-mount autoradiography, a procedure which affords the best available conditions to accurately localize diffusable radiolabeled compounds at cellular and subcellular levels. The overall amount of radioactivity accumulated in neuropil and in neuronal cell bodies was similar in most brain regions examined. Of the regions assessed, the CA3 pyramidal cell field of the hippocampus was the only region in which the radioactivity in cell bodies was notably greater than that of neuropil. In the somatosensory cortex and in the lateral hypothalamus, a wide range of radioactivity was found among individual neurons and among different areas of neuropil. In all brain regions examined, a subpopulation of small cells, with morphological characteristics of glial cells, accumulated [3H]2-DG to a much greater extent than other glial cells or neurons. That finding suggests that certain glial cells are in a markedly higher metabolic state than other brain cells.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
13
pubmed:volume
401
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
43-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Cerebral metabolic mapping at the cellular level with dry-mount autoradiography of [3H]2-deoxyglucose.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't