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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1986-10-8
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pubmed:abstractText |
Methotrexate (MTX) concentrations in erythrocytes in 32 psoriatics treated weekly with MTX p.o. or i.m. have been studied. When treatment had been constant for at least 5 weeks, there was only small variation in erythrocyte MTX (ery-MTX) in the week between two courses of treatment. The ery-MTX was correlated with the weekly dose of MTX. For patients treated with MTX i.m. r = 0.87, and in patients given divided oral doses r was 0.68. There was no difference in ery-MTX between the two routes of administration. No correlation was observed between ery-MTX and the total MTX dose or the length of treatment. During constant MTX administration small variations in ery-MTX were observed. Small changes in the weekly dose of MTX resulted in marked changes in ery-MTX in 4 of the 5 patients studied.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0031-6970
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
453-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3743621-Administration, Oral,
pubmed-meshheading:3743621-Adult,
pubmed-meshheading:3743621-Aged,
pubmed-meshheading:3743621-Drug Administration Schedule,
pubmed-meshheading:3743621-Erythrocytes,
pubmed-meshheading:3743621-Female,
pubmed-meshheading:3743621-Humans,
pubmed-meshheading:3743621-Injections, Intramuscular,
pubmed-meshheading:3743621-Male,
pubmed-meshheading:3743621-Methotrexate,
pubmed-meshheading:3743621-Middle Aged,
pubmed-meshheading:3743621-Psoriasis
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pubmed:year |
1986
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pubmed:articleTitle |
Methotrexate in erythrocytes of patients with psoriasis.
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pubmed:publicationType |
Journal Article
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