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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1987-12-29
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pubmed:abstractText |
Four healthy volunteers and six patients with hydronephrosis underwent magnetic resonance (MR) imaging after the injection of gadolinium-diethylenetriaminepenta-aceticacid for the assessment of renal function. Coronal angulated 10-second images were obtained during suspended respiration (inspiratory apnea) and showed excellent anatomic detail. In healthy volunteers, the renal cortex showed an increase in signal intensity after Gd-DTPA injection, and the renal medulla showed a precipitous decrease in intensity approximately 1 minute after injection, followed by a gradual increase in intensity. The renal pelvis showed a gradual decrease in intensity after several minutes, with occasional signal-void areas in adjacent structures. In patients with hydronephrosis, the decrease in intensity in the medulla and pelvis was not observed; instead, an increase in intensity occurred. The physiologic function of glomerular filtration and in vitro results of serial dilutions of Gd-DTPA suggest that the decrease in intensity is due to T2 and susceptibility effects occurring at high concentrations of Gd-DTPA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0033-8419
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
165
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
837-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3685363-Adult,
pubmed-meshheading:3685363-Aged,
pubmed-meshheading:3685363-Gadolinium,
pubmed-meshheading:3685363-Gadolinium DTPA,
pubmed-meshheading:3685363-Humans,
pubmed-meshheading:3685363-Hydronephrosis,
pubmed-meshheading:3685363-Kidney,
pubmed-meshheading:3685363-Kidney Function Tests,
pubmed-meshheading:3685363-Magnetic Resonance Imaging,
pubmed-meshheading:3685363-Middle Aged,
pubmed-meshheading:3685363-Organometallic Compounds,
pubmed-meshheading:3685363-Pentetic Acid,
pubmed-meshheading:3685363-Reference Values
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pubmed:year |
1987
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pubmed:articleTitle |
Normal and hydronephrotic kidney: evaluation of renal function with contrast-enhanced MR imaging.
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pubmed:affiliation |
Department of Radiology, University Hospital, Zurich, Switzerland.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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