Linked Life Data

3630592

Source:http://linkedlifedata.com/resource/pubmed/id/3630592

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1987-9-29
pubmed:abstractText
At present there is a lack of information concerning haemodynamic changes related to the degree of sympathetic blockade during spinal analgesia. In this investigation, involving 36 patients, changes in haemodynamic parameters were studied in 30 patients receiving spinal analgesia and in six patients having "sham spinal" analgesia. Three local anaesthetic solutions were used: bupivacaine without and with glucose and tetracaine with glucose. Skin conductance responses were used to evaluate changes in provoked sympathetic activity. It was found, as in previous studies, that a complete block of sympathetic activity in the foot was seen in only 60% of patients with an average analgesic level of T4. A partial sympathetic blockade was registered up to and above the level of analgesia. In 25/30 cases only minor alterations in cardiac output, heart rate, stroke volume, mean arterial pressure and systemic vascular resistance were seen in spinal analgesia whose level reached on average T4-5. In five cases in whom analgesia reached T4-3, mean arterial pressure fell greater than or equal to 30% with a well-preserved cardiac output, but with complete sympathetic blockade up to T5 and in two cases also in the hand. Only minor differences were observed between the different anaesthetic solutions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0001-5172
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
467-73
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Sympathetic activity and haemodynamic variables during spinal analgesia in man.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't