Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1987-5-28
pubmed:abstractText
Prolonged resuscitation in adults produces a recognizable pattern of myocardial injury characterized by contraction band necrosis, focal hemorrhage, and coagulation necrosis. To rule out the possibility of these changes being due to ischemia and underlying coronary artery disease, autopsies of 26 children admitted to Stanford from 1981 to 1983 were reviewed. Seventeen had attempted resuscitation with catecholamines and defibrillation; the remainder did not. Sections of myocardium were graded by two observers. For controls, brain-dead heart donors otherwise disease-free and essentially untreated with either defibrillation or beta-active catecholamines were used. Defibrillation alone and catecholamines alone each produced equal amounts of destruction, but using these together resulted in a statistically significant increase in tissue destruction. This suggests that the damaging effects of these agents are synergistic, not additive.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0195-7910
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3-8
pubmed:dateRevised
2011-2-2
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Resuscitation-induced myocardial necrosis. Catecholamines and defibrillation.
pubmed:publicationType
Journal Article