Linked Life Data

3566532

Source:http://linkedlifedata.com/resource/pubmed/id/3566532

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1987-4-27
pubmed:abstractText
Rats fed a normo- or hyper-cholesterolic diet were treated for 7 days with indobufen or ticlopidine hydrochloride (Ticl.HCl) orally, 20 mg/kg/day. At the end of treatment, the animals were perfused in vivo to fix the cell and to dye the intracellular junctions of the endothelial reticulum of the arterial wall. The integrity of the aortic endothelial layer was evaluated microscopically. Rats fed a normo- or hyper-cholesterolic diet, treated with indobufen, did not differ from the control group as regards the parameters in question. The animals treated with Ticl.HCl presented a reticulo-endothelial injury when fed a normo-lipidic diet and smooth muscle cell infiltration, an indicator of more advanced lesion, when fed a hypercholesterolic diet.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0098-6127
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
100-12
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
In vivo effect of indobufen and ticlopidine hydrochloride on aortic endothelial integrity of normo- or hyper-cholesterolemic rats.
pubmed:publicationType
Journal Article