Linked Life Data

3532293

Source:http://linkedlifedata.com/resource/pubmed/id/3532293

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1986-11-19
pubmed:abstractText
A multicenter study was carried out on a total of 574 patients to investigate the safety and efficacy of a 800-mg nighttime dose of cimetidine in comparison with 400 mg twice daily for 4 or 8 weeks in the treatment of patients with duodenal ulcer. No statistically significant differences were observed between the two regimens. Healing rates were as follows: at 4 weeks 212 of 269 patients (79%) healed with the once daily regimen whereas 200 of 270 patients (74%) healed with the twice daily dosage; at 8 weeks 242 of 251 patients (96%) healed with the once daily regimen as compared with 232 of 246 (94%) treated with the twice daily dosage. The dosages were equally effective in relief of pain during the study period. The results confirm that a single nighttime dose of cimetidine is as effective as the twice daily regimen.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0085-5928
pubmed:author
pubmed:issnType
Print
pubmed:volume
121
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
11-6
pubmed:dateRevised
2008-2-13
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Cimetidine, 800 mg once daily: preliminary European clinical data evaluation.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Controlled Clinical Trial