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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1986-9-19
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pubmed:abstractText |
Nineteen of 224 renal allograft recipients who were prospectively randomized to receive either cyclosporine (n = 117) or azathioprine sodium-antilymphocyte globulin (n = 107) for immunosuppression suffered from one period of pneumonia (14 azathioprine and five cyclosporine recipients); two recipients of azathioprine had two episodes. Four patients in the azathioprine group and one in the cyclosporine group died, for mortalities of 3.7% and 0.85%, respectively. The percentage of pneumonia-free patients at one year was 96.3% in the cyclosporine group while it was 90.8% in the azathioprine group. Nondiabetics, women, and recipients of grafts from living related donors were at a statistically lower risk of developing pneumonia when treated with cyclosporine. Viral (cytomegalovirus), fungal (Candida, Aspergillus), and multibacterial causes of pneumonia each occurred with a similar incidence.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0004-0010
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
121
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1056-60
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3527111-Adult,
pubmed-meshheading:3527111-Antilymphocyte Serum,
pubmed-meshheading:3527111-Azathioprine,
pubmed-meshheading:3527111-Clinical Trials as Topic,
pubmed-meshheading:3527111-Cyclosporins,
pubmed-meshheading:3527111-Diabetes Complications,
pubmed-meshheading:3527111-Female,
pubmed-meshheading:3527111-Graft Rejection,
pubmed-meshheading:3527111-Humans,
pubmed-meshheading:3527111-Immunosuppression,
pubmed-meshheading:3527111-Kidney Transplantation,
pubmed-meshheading:3527111-Male,
pubmed-meshheading:3527111-Middle Aged,
pubmed-meshheading:3527111-Pneumonia,
pubmed-meshheading:3527111-Prospective Studies,
pubmed-meshheading:3527111-Random Allocation
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pubmed:year |
1986
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pubmed:articleTitle |
Pulmonary infections. The Minnesota randomized prospective trial of cyclosporine vs azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial
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