Linked Life Data

3514004

Source:http://linkedlifedata.com/resource/pubmed/id/3514004

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1986-5-9
pubmed:abstractText
Evidence is growing that the somatomedins act by a paracrine and/or autocrine mechanism. The importance of these mechanisms relative to the traditional endocrine actions is not clear, and it is possible that these growth factors act through all three mechanisms. Supporting the possible paracrine/autocrine mechanisms are reports that production of somatomedins or somatomedin-like peptides is widespread throughout the body. Additionally, the somatomedins have biological actions on remarkably diverse cell types, and these responsive cells are found in close proximity to cells known to produce somatomedin. Finally, factors that alter the growth rate of cultured cells produce parallel changes in somatomedin secretion, suggesting that these phenomena are closely linked.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0300-595X
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
59-77
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Paracrine functions of somatomedins.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't