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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1988-1-12
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pubmed:abstractText |
Sixteen patients with unilateral subcortical haemorrhagic or ischaemic stroke, confirmed by CT, were evaluated for the presence of aphasia and neglect. Compared with patients without neuropsychological deficits, left brain-damaged aphasic and right brain-damaged neglect patients showed a significantly greater reduction of cortical perfusion on N,N,N1-trimethyl-N1-(2)-hydroxy-3-methyl-5-(I-123) iodobenzyl-1,3-propanediamine 2 HCl I-123 (HIPDM) and single photon emission computerized tomography (SPECT). These results suggest that major cortical derangement is the crucial factor for the appearance of aphasia or neglect after a subcortical stroke. These remote effects, which are related to the size of the subcortical lesion, are interpreted in terms of interruption of neural connections (diaschisis).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0006-8950
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
110 ( Pt 5)
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1211-29
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3499949-Adult,
pubmed-meshheading:3499949-Aged,
pubmed-meshheading:3499949-Aphasia,
pubmed-meshheading:3499949-Cerebrovascular Circulation,
pubmed-meshheading:3499949-Cerebrovascular Disorders,
pubmed-meshheading:3499949-Female,
pubmed-meshheading:3499949-Humans,
pubmed-meshheading:3499949-Male,
pubmed-meshheading:3499949-Middle Aged,
pubmed-meshheading:3499949-Psychomotor Disorders,
pubmed-meshheading:3499949-Tomography, Emission-Computed,
pubmed-meshheading:3499949-Tomography, X-Ray Computed
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pubmed:year |
1987
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pubmed:articleTitle |
Aphasia and neglect after subcortical stroke. A clinical/cerebral perfusion correlation study.
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pubmed:affiliation |
Department of Biomedical Technology, San Raffaele Hospital, University of Milano, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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