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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1986-6-30
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pubmed:abstractText |
High resolution chromosome analysis was performed on bone marrow cells from four patients with acute promyelocytic leukemia and t(15;17), and in lymphocytes from two unrelated, phenotypically normal persons with an apparently identical constitutional translocation. Scrutiny of prophase-prometaphase chromosomes localized the breakpoints in all six cases to subbands 15q22.3 and 17q11.2. Molecular genetic studies have localized the oncogene c-erbA to chromosome #17 between the breakpoints of the constitutional and the acquired anomaly. The present results, therefore, map c-erbA to subband 17q11.2.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0165-4608
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
95-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3458521-Chromosome Aberrations,
pubmed-meshheading:3458521-Chromosome Disorders,
pubmed-meshheading:3458521-Chromosome Mapping,
pubmed-meshheading:3458521-Chromosomes, Human, 13-15,
pubmed-meshheading:3458521-Chromosomes, Human, 16-18,
pubmed-meshheading:3458521-Humans,
pubmed-meshheading:3458521-Leukemia, Myeloid, Acute,
pubmed-meshheading:3458521-Oncogenes,
pubmed-meshheading:3458521-Proto-Oncogenes,
pubmed-meshheading:3458521-Translocation, Genetic
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pubmed:year |
1986
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pubmed:articleTitle |
High resolution chromosome analysis of constitutional and acquired t(15;17) maps c-erbA to subband 17q11.2.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|