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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1986-3-13
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pubmed:abstractText |
We have used hamster cDNA probes for 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase (HMGCR) to determine the chromosomal location of the human gene for HMG CoA reductase. Southern blot analysis of genomic DNA from 16 independent mouse-human somatic cell hybrids showed that the human gene for HMG CoA reductase resides on chromosome 5. Analysis of Chinese hamster-human somatic cell hybrids selectively retaining human 5 or a portion of it showed that the gene locus for HMG CoA reductase can be assigned to the q13----q23 region of chromosome 5.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0740-7750
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
89-94
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3456176-Animals,
pubmed-meshheading:3456176-Cells, Cultured,
pubmed-meshheading:3456176-Chromosome Banding,
pubmed-meshheading:3456176-Chromosome Mapping,
pubmed-meshheading:3456176-Chromosomes, Human, 4-5,
pubmed-meshheading:3456176-DNA,
pubmed-meshheading:3456176-Electrophoresis, Agar Gel,
pubmed-meshheading:3456176-Genes,
pubmed-meshheading:3456176-Humans,
pubmed-meshheading:3456176-Hybrid Cells,
pubmed-meshheading:3456176-Hydroxymethylglutaryl CoA Reductases,
pubmed-meshheading:3456176-Mice
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pubmed:year |
1986
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pubmed:articleTitle |
Assignment of human 3-hydroxy-3-methylglutaryl coenzyme A reductase gene to q13----q23 region of chromosome 5.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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