Linked Life Data

3427405

Source:http://linkedlifedata.com/resource/pubmed/id/3427405

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1988-3-7
pubmed:abstractText
Flicker sensitivity and spatial contrast sensitivity (CS) were examined in a total of 99 patients with Parkinson's disease (PD). All patients were undergoing treatment with dopaminergic agents. Specific losses in sensitivity observed in PD were (1) a loss in flicker sensitivity which was most pronounced around the peak of the function (8 Hz) and (2) a loss near the peak of the spatial CS curve, often with no noticeable low frequency attenuation. Several PD patients affected by the 'on-off' syndrome were tested in both 'on' and 'off' phases, and the results show that the CS function switches in parallel with motor symptoms of the disease. These data suggest that not only is the visual system affected in PD, but that dopamine may have an essential role in receptive field organization in human vision.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0006-8950
pubmed:author
pubmed:issnType
Print
pubmed:volume
110 ( Pt 6)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1675-98
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Visual dysfunction in Parkinson's disease. Loss in spatiotemporal contrast sensitivity.
pubmed:affiliation
Department of Neurology, Mount Sinai School of Medicine of the City University of New York, NY.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.