Linked Life Data

3416737

Source:http://linkedlifedata.com/resource/pubmed/id/3416737

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7-8
pubmed:dateCreated
1988-10-24
pubmed:abstractText
Twenty-five courses of oral ciprofloxacin were administered to 16 patients experiencing pulmonary exacerbations of cystic fibrosis in an open, uncontrolled trial of efficacy and tolerance. Patients were treated for 7-35 days and efficacy was evaluated based on changes in clinical score, white blood cell count, quantitative bacteriology of sputum, and pulmonary function tests. Most courses of therapy were associated with a positive response with changes in clinical score and forced expiratory volume in one second being statistically significant (p less than 0.05). No side effects to ciprofloxacin were noted. Emergence of bacterial resistance to ciprofloxacin was rare. Ciprofloxacin appears to be effective in patients with cystic fibrosis who are experiencing pulmonary exacerbations associated with susceptible bacterial pathogens.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0012-6578
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
551-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Efficacy of ciprofloxacin in patients with cystic fibrosis.
pubmed:affiliation
Department of Pharmacy Practice, College of Pharmacy, University of Utah, Salt Lake City 84112.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't