Linked Life Data

3400685

Source:http://linkedlifedata.com/resource/pubmed/id/3400685

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1B
pubmed:dateCreated
1988-9-7
pubmed:abstractText
Nocturnal wheezing is a major component of asthma. This article reviews the many factors (allergen exposure, sleep, airway cooling, diminished clearance of mucous secretions) that have been identified as contributing to nocturnal asthma. Also discussed are recent data suggesting that diurnal variations in hormone concentrations and in autonomic nervous system control are possible mechanisms of nocturnal asthma. Decreased epinephrine secretion and increased vagal tone during sleep not only cause airway obstruction but may also enhance bronchial reactivity. These changes in the modulation of airway smooth muscle tone produce bronchial obstruction, which, in turn, accentuates ventilation-perfusion mismatch and increases hypoxia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0002-9343
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
85
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
24-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Pathogenesis and pathophysiology of nocturnal asthma.
pubmed:affiliation
Department of Medicine, University of Wisconsin Medical School, Madison 53792.
pubmed:publicationType
Journal Article