Linked Life Data

3384181

Source:http://linkedlifedata.com/resource/pubmed/id/3384181

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1988-8-4
pubmed:abstractText
The relationship between the HLA system and non-insulin-dependent diabetes mellitus (NIDDM) in South African Indians, a migrant Indian group, was evaluated by testing HLA-A, -B, and -C antigens in 184 patients and 1444 control subjects and HLA-DR antigens in 104 patients and 330 control subjects. There was a significant increase in the frequency of HLA-Bw61 in patients compared with control subjects (27.7 vs. 18%, P = .00155), although the degree of association was not very strong (relative risk 1.7). A similar association has been noted in Fiji Indians, another migrant Indian group. However, no relationship could be established at the DR locus. It is suggested that the relatively high frequency of the Bw61 allele in South African Indians could, in the presence of some environmental factor like obesity, confer increased susceptibility to NIDDM.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0012-1797
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
796-9
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
HLA class I and II antigens in South African Indians with NIDDM.
pubmed:affiliation
Department of Medicine, University of Natal, South Africa.
pubmed:publicationType
Journal Article