Linked Life Data

3366523

Source:http://linkedlifedata.com/resource/pubmed/id/3366523

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-6-16
pubmed:abstractText
In a group of 47 healthy men aged 25-55, the influence of moderate, exhaustive, and prolonged exercise on blood platelet function, coagulation, and fibrinolytic activity was evaluated. Static exertion of short duration and moderate intensity did not cause significant alterations in any of the indices analyzed. Prolonged exercise (60 min) performed on a bicycle ergometer in aerobic conditions led to strong activation of the fibrinolytic system [euglobulin lysis time (ELT) fell from 208 to 88 min] and a slight increase in platelet count (PC) but did not cause significant changes in platelet factor 4 (PF 4) and platelet aggregate ratio, recalcification (RT), and prothrombin time (PT). Repeated bouts of maximum exercise leading to considerable acidosis (pH = 7.22; BE = -13.3) caused a significant increase in blood platelet count and an increase in PF 4 release. These changes were accompanied by strong intensification in fibrinolytic activity (over 63% reduction of ELT and a marked increase of fibrin/fibrinogen degradation products). In some individuals, unfavorable hemostatic changes were observed following intensive exercise. It is concluded that more attention should be given in future to the problem of verification of preventive and rehabilitative training programs from the point of view of exercise-induced hemostatic changes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0172-4622
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
67-72
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Changes in blood platelet function, coagulation, and fibrinolytic activity in response to moderate, exhaustive, and prolonged exercise.
pubmed:affiliation
Department of Sports Medicine, Medical Academy, Lodz, Poland.
pubmed:publicationType
Journal Article, Comparative Study