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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1988-10-12
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pubmed:abstractText |
An inhibitor of polyadenosine diphosphoribose polymerase, 3-aminobenzamide, had no effect on survival or mutagenesis in Chinese hamster ovary cells exposed to X-rays or u.v. light. After exposure to methyl methanesulfonate, 3-aminobenzamide increased cell killing and mutagenesis at the 6-thio-guanine-resistance locus, but had no effect on mutagenesis at the ouabain-resistance locus. These results are consistent with the greater role played by polyadenosine diphosphoribose in cells damaged by alkylating agents rather than by radiations.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0267-8357
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
1
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
237-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3331665-Animals,
pubmed-meshheading:3331665-Benzamides,
pubmed-meshheading:3331665-Cell Line,
pubmed-meshheading:3331665-Cell Survival,
pubmed-meshheading:3331665-Cricetinae,
pubmed-meshheading:3331665-Cricetulus,
pubmed-meshheading:3331665-Methyl Methanesulfonate,
pubmed-meshheading:3331665-Mutation,
pubmed-meshheading:3331665-Radiation-Protective Agents,
pubmed-meshheading:3331665-Ultraviolet Rays,
pubmed-meshheading:3331665-X-Rays
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pubmed:year |
1986
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pubmed:articleTitle |
Mutation frequencies from X-rays, ultraviolet light, and methyl methanesulfonate in Chinese hamster ovary cells incubated with 3-aminobenzamide.
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pubmed:affiliation |
Laboratory of Radiobiology and Environmental Health, University of California, San Francisco 94143.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|