Linked Life Data

3296647

Source:http://linkedlifedata.com/resource/pubmed/id/3296647

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1987-7-20
pubmed:abstractText
Intracranial arterial blood flow velocities were studied before and after ductus closure by surgery (n = 8) and indomethacin (n = 10) in very low birth weight infants. Blood flow velocities were measured non-invasively through the fontanel with a pulsed Doppler velocimeter. Ligation of the ductus was associated with a 62% increase in mean flow velocity 24 hours after surgery, mainly secondary to increased diastolic flow velocity. Indomethacin (0.2 mg/kg i.v.) induction of ductus constriction was associated with a 36% decrease of mean flow velocity one hour after administration. At 24 hours, the intracranial blood flow velocity had returned to the pretreatment level but was still significantly lower than after ligation. Ductus closure is associated with marked changes in cerebral hemodynamics. Ligation causes increased arterial blood flow velocities and indomethacin administration seems to reduce blood flow velocities to the brain.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-8843
pubmed:author
pubmed:issnType
Print
pubmed:volume
329
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
140-7
pubmed:dateRevised
2008-2-20
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Ductus closure in preterm infants. Effects on cerebral hemodynamics.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't