Linked Life Data

328782

Source:http://linkedlifedata.com/resource/pubmed/id/328782

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1977-9-17
pubmed:abstractText
Soluble FcR-like material can be demonstrated in the culture supernatants of activated lymphocytes. We modified as assay for its detection which was based upon inhibition of complement dependent hemolysis, an unreliable phenomenon in our hands. The micromethod presented was developed using the culture supernatants of FcR producing and FcR non-producing lymphoblastoid cell lines. Suppression of hemolysis was consistently observed providing the assay was performed below 22 degrees C. It is suggested that the classical pathway of complement activation is inhibited by this material but not the alternative pathway. By this method FcR material can be detected in small cultures where cells are limited in number.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0022-1759
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
111-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Modified micromethod for detection of human Fc receptor-like material.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.