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pubmed-article:3260986pubmed:abstractTextFollowing MPTP administration, 4 Cynomolgus monkeys developed a parkinsonian syndrome, accompanied by specific changes of both pattern visual evoked potential and electroretinogram. Retinal dopamine and dihydroxyphenylacetic acid contents were measured in the 4 MPTP-treated monkeys and in 3 normal monkeys. Dopamine and dihydroxyphenylacetic acid levels were significantly lower in the retinas of the MPTP-treated animals (p less than 0.001), suggesting that dopamine has a specific function in the visual system of primates.lld:pubmed
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pubmed-article:3260986pubmed:articleTitleSystemic 1-methyl,4-phenyl,1-2-3-6-tetrahydropyridine (MPTP) administration decreases retinal dopamine content in primates.lld:pubmed
pubmed-article:3260986pubmed:affiliationDept. of Neurology, Mount Sinai School of Medicine, New York, N.Y. 10029.lld:pubmed
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pubmed-article:3260986pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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