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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1988-8-31
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pubmed:abstractText |
Following MPTP administration, 4 Cynomolgus monkeys developed a parkinsonian syndrome, accompanied by specific changes of both pattern visual evoked potential and electroretinogram. Retinal dopamine and dihydroxyphenylacetic acid contents were measured in the 4 MPTP-treated monkeys and in 3 normal monkeys. Dopamine and dihydroxyphenylacetic acid levels were significantly lower in the retinas of the MPTP-treated animals (p less than 0.001), suggesting that dopamine has a specific function in the visual system of primates.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0024-3205
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
255-62
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3260986-1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine,
pubmed-meshheading:3260986-3,4-Dihydroxyphenylacetic Acid,
pubmed-meshheading:3260986-Animals,
pubmed-meshheading:3260986-Chromatography, Liquid,
pubmed-meshheading:3260986-Dopamine,
pubmed-meshheading:3260986-Electroretinography,
pubmed-meshheading:3260986-Evoked Potentials, Visual,
pubmed-meshheading:3260986-Female,
pubmed-meshheading:3260986-Macaca fascicularis,
pubmed-meshheading:3260986-Parkinson Disease, Secondary,
pubmed-meshheading:3260986-Pattern Recognition, Visual,
pubmed-meshheading:3260986-Pyridines,
pubmed-meshheading:3260986-Retina
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pubmed:year |
1988
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pubmed:articleTitle |
Systemic 1-methyl,4-phenyl,1-2-3-6-tetrahydropyridine (MPTP) administration decreases retinal dopamine content in primates.
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pubmed:affiliation |
Dept. of Neurology, Mount Sinai School of Medicine, New York, N.Y. 10029.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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