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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1988-2-23
|
| pubmed:abstractText |
We compared rates of antibiotic resistance in strains of Streptococcus pneumoniae recovered from nasopharyngeal secretions of a group of children studied longitudinally in a research day care center between 1978 and 1985 and recovered from usually sterile body fluids of patients at a tertiary care hospital between 1981 and 1985. The prevalence of trimethoprim-sulfamethoxazole (TMP-SMZ) resistance was 11.5% in isolates from the hospital, whereas 30.0% of episodes of nasopharyngeal carriage of S. pneumoniae studied in day care children included TMP-SMZ-resistant isolates. The proportion of episodes of colonization with TMP-SMZ-resistant isolates in the day care study increased from 5.4% before 1981 to 39% between 1981 and 1985. Isolates of S. pneumoniae relatively resistant (MIC greater than or equal to 0.125 micrograms/mL) to penicillin G, amoxicillin, or cefuroxime accounted for 8% of isolates from the hospital and 11.9% of episodes of nasopharyngeal colonization in children in day care. Pneumococci with reduced susceptibility to either TMP-SMZ or a beta-lactam antibiotic were recovered from 68% of 72 children in the day care study.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amoxicillin,
http://linkedlifedata.com/resource/pubmed/chemical/Cefuroxime,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfamethoxazole,
http://linkedlifedata.com/resource/pubmed/chemical/Trimethoprim,
http://linkedlifedata.com/resource/pubmed/chemical/Trimethoprim-Sulfamethoxazole...
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0022-1899
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
157
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
256-63
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:3257247-Amoxicillin,
pubmed-meshheading:3257247-Carrier State,
pubmed-meshheading:3257247-Cefuroxime,
pubmed-meshheading:3257247-Child, Preschool,
pubmed-meshheading:3257247-Child Day Care Centers,
pubmed-meshheading:3257247-Drug Combinations,
pubmed-meshheading:3257247-Drug Resistance, Microbial,
pubmed-meshheading:3257247-Humans,
pubmed-meshheading:3257247-Infant,
pubmed-meshheading:3257247-Longitudinal Studies,
pubmed-meshheading:3257247-Nasopharynx,
pubmed-meshheading:3257247-Penicillin Resistance,
pubmed-meshheading:3257247-Pneumococcal Infections,
pubmed-meshheading:3257247-Streptococcus pneumoniae,
pubmed-meshheading:3257247-Sulfamethoxazole,
pubmed-meshheading:3257247-Trimethoprim,
pubmed-meshheading:3257247-Trimethoprim Resistance,
pubmed-meshheading:3257247-Trimethoprim-Sulfamethoxazole Combination
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Nasopharyngeal carriage of antibiotic-resistant pneumococci by children in group day care.
|
| pubmed:affiliation |
Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill 27514.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|