Linked Life Data

3147181

Source:http://linkedlifedata.com/resource/pubmed/id/3147181

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5-6
pubmed:dateCreated
1989-4-5
pubmed:abstractText
The possibility of intraperitoneal (IP) parenteral nutrition was suggested after the observation that glucose and amino acids pass from the peritoneal cavity into the systemic circulation. We used rabbits to study the characteristics of the transfer of glucose, lipids and amino acids. An IP injection of glucose 25% (1 g/kg) produced a peak level in the serum within 40 min. A 20% fat solution (1 g/kg) showed maximum serum levels of triglycerides and total lipid in 2.5 h, while a standard amino acid solution (1.5 g/kg) enriched with 25 14C-phenylalanine peaked serum levels in 16 min. The 4 rabbits survived for 28 days with IP glucose, amino acids and lipids as the only form of nutrition, apart from water. When sacrificed after 28 days histology of peritoneum, liver, spleen, gut and kidney showed no abnormality. We conclude that the basic nutritional components are adequately absorbed through the peritoneum, and that long-term nutritional support can be achieved uneventfully with IP administration of nutritional solutions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0014-312X
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
352-7
pubmed:dateRevised
2006-11-30
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Total parenteral nutrition by intraperitoneal feeding in rabbits.
pubmed:affiliation
Department of Surgery, University of Patras, Greece.
pubmed:publicationType
Journal Article