| pubmed-article:3102246 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3102246 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3102246 | lifeskim:mentions | umls-concept:C0003323 | lld:lifeskim |
| pubmed-article:3102246 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:3102246 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:3102246 | lifeskim:mentions | umls-concept:C0079717 | lld:lifeskim |
| pubmed-article:3102246 | lifeskim:mentions | umls-concept:C0035253 | lld:lifeskim |
| pubmed-article:3102246 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
| pubmed-article:3102246 | lifeskim:mentions | umls-concept:C0439851 | lld:lifeskim |
| pubmed-article:3102246 | lifeskim:mentions | umls-concept:C1552596 | lld:lifeskim |
| pubmed-article:3102246 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:3102246 | lifeskim:mentions | umls-concept:C1947931 | lld:lifeskim |
| pubmed-article:3102246 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:3102246 | pubmed:dateCreated | 1987-3-30 | lld:pubmed |
| pubmed-article:3102246 | pubmed:abstractText | Activated T lymphocytes can provide all of the signals necessary to induce the proliferation of resting B lymphocytes. The activation signal is presumably initiated through direct T-B lymphocyte contact. The role of the leukocyte function antigen-1 (LFA-1) and T4 molecules in the activation of purified, small B lymphocytes by mitomycin C-treated T lymphocytes was examined by using monoclonal antibodies that react with and inhibit the function of these molecules. Anti-LFA-1 antibody binding significantly inhibited T-B lymphocyte interactions that result in B lymphocyte proliferation. In contrast, the presence of anti-T4 antibodies at concentrations as high as 100 micrograms/ml did not inhibit this interaction. These results indicate that the B lymphocyte activation signal may not be mediated through the interaction of T4 molecules with major histocompatibility complex class II antigens of the B lymphocyte but is a cell-cell contact-dependent event that is facilitated by LFA-1 molecules. | lld:pubmed |
| pubmed-article:3102246 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3102246 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3102246 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3102246 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3102246 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3102246 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3102246 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3102246 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3102246 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3102246 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3102246 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3102246 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:3102246 | pubmed:issn | 0014-2980 | lld:pubmed |
| pubmed-article:3102246 | pubmed:author | pubmed-author:SchlossmanS... | lld:pubmed |
| pubmed-article:3102246 | pubmed:author | pubmed-author:SchmidtR ERE | lld:pubmed |
| pubmed-article:3102246 | pubmed:author | pubmed-author:RitzJJ | lld:pubmed |
| pubmed-article:3102246 | pubmed:author | pubmed-author:RuddC ECE | lld:pubmed |
| pubmed-article:3102246 | pubmed:author | pubmed-author:TedderT FTF | lld:pubmed |
| pubmed-article:3102246 | pubmed:author | pubmed-author:KornackiM MMM | lld:pubmed |
| pubmed-article:3102246 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3102246 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:3102246 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3102246 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3102246 | pubmed:pagination | 1539-43 | lld:pubmed |
| pubmed-article:3102246 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:3102246 | pubmed:meshHeading | pubmed-meshheading:3102246-... | lld:pubmed |
| pubmed-article:3102246 | pubmed:meshHeading | pubmed-meshheading:3102246-... | lld:pubmed |
| pubmed-article:3102246 | pubmed:meshHeading | pubmed-meshheading:3102246-... | lld:pubmed |
| pubmed-article:3102246 | pubmed:meshHeading | pubmed-meshheading:3102246-... | lld:pubmed |
| pubmed-article:3102246 | pubmed:meshHeading | pubmed-meshheading:3102246-... | lld:pubmed |
| pubmed-article:3102246 | pubmed:meshHeading | pubmed-meshheading:3102246-... | lld:pubmed |
| pubmed-article:3102246 | pubmed:meshHeading | pubmed-meshheading:3102246-... | lld:pubmed |
| pubmed-article:3102246 | pubmed:meshHeading | pubmed-meshheading:3102246-... | lld:pubmed |
| pubmed-article:3102246 | pubmed:meshHeading | pubmed-meshheading:3102246-... | lld:pubmed |
| pubmed-article:3102246 | pubmed:meshHeading | pubmed-meshheading:3102246-... | lld:pubmed |
| pubmed-article:3102246 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3102246 | pubmed:articleTitle | Function of the LFA-1 and T4 molecules in the direct activation of resting human B lymphocytes by T lymphocytes. | lld:pubmed |
| pubmed-article:3102246 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3102246 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3102246 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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