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pubmed:abstractText |
A case of severe dialysis encephalopathy is reported, in which the autopsy finding of an extensive spongiform change in areas of the cortex directly corresponded to high aluminium-concentration in these areas, supporting the theory of an aetiological role for aluminium. A therapeutic approach combining low aluminium intake and removal of aluminium by a chelating agent (desferrioxamine) is promising, but more precise guidelines are needed.
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