| pubmed-article:3053331 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3053331 | lifeskim:mentions | umls-concept:C0043393 | lld:lifeskim |
| pubmed-article:3053331 | lifeskim:mentions | umls-concept:C0032136 | lld:lifeskim |
| pubmed-article:3053331 | lifeskim:mentions | umls-concept:C0008633 | lld:lifeskim |
| pubmed-article:3053331 | lifeskim:mentions | umls-concept:C1522642 | lld:lifeskim |
| pubmed-article:3053331 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:3053331 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:3053331 | lifeskim:mentions | umls-concept:C0079866 | lld:lifeskim |
| pubmed-article:3053331 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:3053331 | pubmed:dateCreated | 1988-12-22 | lld:pubmed |
| pubmed-article:3053331 | pubmed:abstractText | The cells of Saccharomyces cerevisiae were transformed by plasmid pYG-007 treated in vitro with o-methylhydroxylamine. The plasmid consists of a portion of the bacterial plasmid with genes of resistance to ampicillin, chloramphenicol and tetracycline, 2 mkm yeast DNA and yeast genes ADE2 and LEU2. The collection of mutants containing a mutant allele of ADE2 gene within the plasmid was obtained. Interallelic complementation and that induced by suppression were studied in these ade 2 mutants. It was shown that all these induced ade 2 mutations were base-pair substitutions. Using the mechanism of conversion we managed to transfer the plasmid ade 2 mutations into the chromosome. Three pairs of strains carrying similar mutation in plasmid and chromosome were created. Analysis of frequency of reversions induced by UV-light and hydroxylaminopurine in the mutant ade2 locus comprised in the plasmid and chromosome showed that the former induced reversions in plasmid alleles less effectively than the latter. | lld:pubmed |
| pubmed-article:3053331 | pubmed:language | rus | lld:pubmed |
| pubmed-article:3053331 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3053331 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3053331 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3053331 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3053331 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3053331 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3053331 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:3053331 | pubmed:issn | 0016-6758 | lld:pubmed |
| pubmed-article:3053331 | pubmed:author | pubmed-author:FedorovaI VIV | lld:pubmed |
| pubmed-article:3053331 | pubmed:author | pubmed-author:KorolevV GVG | lld:pubmed |
| pubmed-article:3053331 | pubmed:author | pubmed-author:GrachevaL MLM | lld:pubmed |
| pubmed-article:3053331 | pubmed:author | pubmed-author:KasinovaG VGV | lld:pubmed |
| pubmed-article:3053331 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3053331 | pubmed:volume | 24 | lld:pubmed |
| pubmed-article:3053331 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3053331 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3053331 | pubmed:pagination | 1178-86 | lld:pubmed |
| pubmed-article:3053331 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3053331 | pubmed:meshHeading | pubmed-meshheading:3053331-... | lld:pubmed |
| pubmed-article:3053331 | pubmed:meshHeading | pubmed-meshheading:3053331-... | lld:pubmed |
| pubmed-article:3053331 | pubmed:meshHeading | pubmed-meshheading:3053331-... | lld:pubmed |
| pubmed-article:3053331 | pubmed:meshHeading | pubmed-meshheading:3053331-... | lld:pubmed |
| pubmed-article:3053331 | pubmed:meshHeading | pubmed-meshheading:3053331-... | lld:pubmed |
| pubmed-article:3053331 | pubmed:meshHeading | pubmed-meshheading:3053331-... | lld:pubmed |
| pubmed-article:3053331 | pubmed:meshHeading | pubmed-meshheading:3053331-... | lld:pubmed |
| pubmed-article:3053331 | pubmed:meshHeading | pubmed-meshheading:3053331-... | lld:pubmed |
| pubmed-article:3053331 | pubmed:meshHeading | pubmed-meshheading:3053331-... | lld:pubmed |
| pubmed-article:3053331 | pubmed:meshHeading | pubmed-meshheading:3053331-... | lld:pubmed |
| pubmed-article:3053331 | pubmed:meshHeading | pubmed-meshheading:3053331-... | lld:pubmed |
| pubmed-article:3053331 | pubmed:meshHeading | pubmed-meshheading:3053331-... | lld:pubmed |
| pubmed-article:3053331 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3053331 | pubmed:articleTitle | [Mutagenesis on cloned yeast genes. The mutation of the yeast gene comprising the plasmid and chromosome]. | lld:pubmed |
| pubmed-article:3053331 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3053331 | pubmed:publicationType | English Abstract | lld:pubmed |
