Linked Life Data

3025086

Source:http://linkedlifedata.com/resource/pubmed/id/3025086

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1987-2-19
pubmed:abstractText
The phenotype of the human effector leukocyte subset involved in production of alpha interferon was examined using positive and negative selection techniques including murine monoclonal antibodies. The data suggest that the effector cell responsible for the elaboration of human alpha interferon is surface immunoglobulin positive, lacks either the E-rosette receptor or any monocyte determinants and is also negative for expression of the surface antigens identified by Leu-10 and Leu-11b monoclonal antibodies. Neither monocytes nor polymorphonuclear leukocytes were shown to play a role in regulation or production of alpha interferon. The data further imply, however, that the Leu-7+, large granular lymphocyte subpopulation may play a critical role in regulating human alpha interferon production by surface immunoglobulin positive B cell effectors.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0882-0139
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
559-74
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Characterization of non-T effector cell subpopulations involved in production of human alpha interferon.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.