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pubmed-article:3002848pubmed:abstractTextOn the basis of the reported slow channel-inhibiting activity of oximes and phosphonates a series of compounds bearing such functions on lipophilic carriers were synthesized and studied. Among the compounds studied only (VI b) shows a slight cardiovascular activity. The surprising lack of activity of diethyl 3,4-dimethoxybenzyl-phosphonate (XIV), which is closely related to Fostedil, is discussed.lld:pubmed
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pubmed-article:3002848pubmed:articleTitleSearch for new Ca++ antagonists. Lipophilic oximes and phosphonates.lld:pubmed
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